产品货号：
Z36645
中文名称：
RAGE/AGER抗体
英文名称：
Anti-RAGE/AGER Antibody (Clone#5C6C1)
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-RAGE/AGER Antibody (Clone#5C6C1) |
| 指标别名 | AGER;RAGE |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,FCM |
| 基因名称 | AGER |
| 克隆号 | 5C6C1 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG2b |
| 免疫原 | A synthetic peptide corresponding to a sequence at the N-terminus of human RAGE (91-120aa IQDEGIFRCQAMNRNGKETKSNYRVRVYQI),different from the related mouse and rat sequences by six amino acids. |
| 实际分子量 | 43KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | The receptor for advanced glycation end products (RAGE) is a multi-ligand member of the immunoglobulin superfamily of cell surface molecules.It interacts with distinct molecules implicated in homeostasis,development and inflammation,and certain diseases such as diabetes and Alzheimer's disease.RAGE is also a central cell surface receptor for amphoterin and EN-RAGE.And RAGE is associated with sustained NF-kappaB activation in the diabetic microenvironment and has a central role in sensory neuronal dysfunction.Moreover,RAGE propagates cellular dysfunction in several inflammatory disorders and diabetes,and it also functions as an endothelial adhesion receptor promoting leukocyte recruitment. |
| Uniprot ID | Q15109 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (ZN1928) for Western blot,and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (ZN1866) for IHC(P). |
| 基因名全称 | advanced glycosylation end product-specific receptor |
| 蛋白名全称 | Advanced glycosylation end product-specific receptor |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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